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Hypocretins neural systems physiology and psychiatric disorders

2019-08-22 02:03

Orexins (hypocretins) directly interact with neuropeptide Y, POMC and glucoseresponsive neurons to regulate Ca 2 signaling in a reciprocal manner to leptin: orexigenic neuronal pathways inAppetite results from the integration of metabolic and hormonal signals within the central nervous system. , Orexinhypocretin in psychiatric disorders: present state of Allison Fusilier, Aidan MeadorWoodruff and Karen L. Gamble, Circadian regulation of membrane physiology in neural oscillators throughout the hypocretins neural systems physiology and psychiatric disorders

Dec 10, 2009  Orexinhypocretin in psychiatric disorders: present state of knowledge and future potential The hypocretins as sensors for metabolism and arousal. Neural Systems, Physiology

Hypocretins, Neural Systems, Physiology, and Psychiatric Disorders Article (PDF Available) in Current Psychiatry Reports 18(1) January 2016 with 148 Reads DOI: Orexinhypocretin in psychiatric disorders: Present state of knowledge and future potential Hypocretins, Neural Systems, Physiology, and Psychiatric Disorders between these systems hypocretins neural systems physiology and psychiatric disorders Feb 01, 2016 Importantly, interruption of the interactions between these systems has the potential to cause neurological and psychiatric diseases. Here, we review the modulation of diverse neural systems by Hcrts and summarize potential therapeutic strategies based on our understanding of the Hcrt system's role in physiology and pathophysiological processes.

Start studying Medical Terminology Chapter 10: The Nervous System and Mental Health Learning Exercise. Learn vocabulary, terms, and more with flashcards, games, and other study tools. hypocretins neural systems physiology and psychiatric disorders Hypocretins and other sleepwake, neurologic and psychiatric disorders. Table 1 summarizes reports in the literature on low and undetectable CSF hypocretin1 levels in patients with sleepwake and neurological disorders. Sleepwake disorders (other than narcolepsy) There may be involvement of the hypocretinorexin system in other disorders of sleep such as primary hypersomnolence, insomnia, and the KleineLevin syndrome 10, and a potential role in sleep disorders affecting the ageing population 7, 28, 41, 51, 52. The role of these peptides in other neurological and psychiatric disorders remains putative. Neurodevelopmental Disorders and Mental Illness. Mental illnesses are nervous system disorders that result in problems with thinking, mood, or relating with other people. These disorders are severe enough to affect a persons quality of life and often make it Importantly, interruption of the interactions between these systems has the potential to cause neurological and psychiatric diseases. Here, we review the modulation of diverse neural systems by Hcrts and summarize potential therapeutic strategies based on our understanding of the Hcrt systems role in physiology and pathophysiological processes.

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