Drugs acting on renin angiotensin aldosterone system

2019-09-18 17:28

In addition to the mechanisms depicted, angiotensin II can raise blood pressure by (1) acting on the distal nephron to promote reabsorption of sodium and (2) increasing vasoconstriction by three mechanisms: promoting release of norepinephrine from sympathetic nerves; promoting release of epinephrine from the adrenal medulla; and acting in the central nervous system to increaseSep 23, 2015 Drugs acting on Renin Angiotensin Aldosterone system. ACE inhibitors are contraindicated during pregnancy because of the risk of fetal hypotension, anuria, and renal failure, sometimes associated with fetal malformations or death. 6. Minor toxic effects seen more typically include altered sense of taste, allergic skin rashes, and drug fever, drugs acting on renin angiotensin aldosterone system

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Chapter 44 Drugs Acting on the System quiz. Awarded 1. 0 points out of 1. 0 possible points. ID: The nurse is caring for a patient with bipolar disorder treated with lithium [Eskalith. The patient has a new prescription for captopril [Capoten for hypertension. Renin activity inhibited by renin inhibitors; ACE inhibited by ACE inhibitors; Angiotensin II receptors inhibited by AT 1receptor antagonists; Aldosterone receptors inhibited by aldosteronereceptor antagonists; No RAASaffecting drugs should be used in pregnant women. drugs acting on renin angiotensin aldosterone system Drugs acting on renin angiotensin system are: Angiotensin Converting Enzyme (ACE) Inhibitors. Enalapril is a prodrug, which is converted into enalaprilat in liver (active metabolite). Its duration of action is prolonged because of the active metabolite (24 hours). It is given in a dose of 5 mg which can be increased up to 40 mg.

Inhibiting the AT 1 R Liver Angiotensinogen Angiotensin I Angiotensin II Kidney Renin DRI Chymase ARB BK Breakdown products ACTH K MR Aldosterone MRA Corticosteroids blocker Adrenal gland DRI, direct renin inhibitor; ARB, angiotensin receptor blocker; MRA, mineralocorticoid receptor antagonist; drugs acting on renin angiotensin aldosterone system Drugs acting on the system. The ACE inhibitors, available for more than three decades, have established roles in the treatment of hypertension, heart failure, and diabetic nephropathy; in addition, these drugs are indicated for myocardial infarction and prevention of cardiovascular events in patients at risk. Chapter 44: Drugs acting on ReninAngiotensin Aldosterone System (RAAS) Drugs that prevent activation of angiotension II by ACE, prevents vasoconstriction that would be produced by angiotensin II, so net effect is vasodilation. prevents remodeling (heart damage due to cellular changes. Prevents Nawater retention that would be meditated by aldosterone. Oct 26, 2017 Drugs Acting on System (RAAS) . The drugs which alter the functioning of System (RAAS) comes under this category and are employed in the management of hypertension and various cardiovascular disorders.

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